Ligand Based CoMFA, CoMSIA and HQSAR Analysis of CCR5 Antagonists
نویسندگان
چکیده
منابع مشابه
Structural investigations of CXCR2 receptor antagonists by CoMFA, CoMSIA and flexible docking studies.
Three-dimensional quantitative structure activity relationship (3D QSAR) analysis was carried out on a et of 56 N,N'-diarylsquaramides, N,N'-diarylureas and diaminocyclobutenediones in order to understand their antagonistic activities against CXCR2. The studies included comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA). Models with good ...
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ژورنال
عنوان ژورنال: Bulletin of the Korean Chemical Society
سال: 2010
ISSN: 0253-2964
DOI: 10.5012/bkcs.2010.31.10.2761